“I’m jazzed.”
Those were the words describing the state of Alzheimer’s disease research from Arthur Toga, PhD, a pioneering neuroscientist and director of the Laboratory of Neuro Imaging (LONI) and the Mark and Mary Stevens Neuroimaging and Informatics Institute at the University of Southern California (USC). He joined Maria Shriver and the Women’s Alzheimer’s Movement (WAM) at Cleveland Clinic team for a learning lunch on September 23rd.
Dr. Toga has focused his research on brain imaging for over 20 years, creating detailed brain maps, developing advanced techniques, and applying these methods to study various brain disorders. He has also built large databases that combine genetic, imaging, clinical, and behavioral data to support research on conditions like Alzheimer’s disease, Huntington’s, and Parkinson’s disease. During the lunch, Dr. Toga shared updates on his work, including the “multiple hit theory,” which suggests that the accumulation of “hits” to brain health, such as injuries and hormonal changes, could explain the higher prevalence of Alzheimer’s disease in women.
The discussion also touched on exciting recent advancements in Alzheimer’s disease research, including blood-based biomarkers and monoclonal antibody treatments, which are poised to transform early detection and treatment, potentially allowing those from future generations affected by the disease to lead relatively normal lives.